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Octreotide and low-fat breast milk in postoperative chylothorax
Mohamed A Hamdan1, Mary Lou Gaeta
1Department of Pediatrics, King Abdulaziz Medical City, Al Ahsa, Saudi Arabia. hamdanma@ngha.med.sa
Insights
Chylothorax, a rare complication after cavo-pulmonary connection in infants, can be severe. This case report details successful treatment using octreotide and low-fat breast milk for refractory chylothorax.
Area of Science:
- Pediatric Cardiology
- Thoracic Surgery
- Neonatal Medicine
Background:
- Chylothorax is a rare but serious complication following cavo-pulmonary connection surgery in infants.
- This condition can lead to significant morbidity and challenges in management.
- Conventional conservative and surgical treatments are often insufficient for severe cases.
Observation:
- A 3-month-old infant developed severe chylothorax post-bilateral cavo-pulmonary connection.
- The infant's condition was refractory to standard treatment modalities.
- This indicated a need for alternative therapeutic strategies.
Findings:
- A combination therapy of parenteral octreotide and low-fat breast milk was administered.
- This novel approach led to the resolution of the severe chylothorax.
- The treatment demonstrated efficacy in a previously refractory case.
Implications:
- Parenteral octreotide combined with dietary modification offers a promising treatment for refractory chylothorax post-cavo-pulmonary connection.
- This approach may improve outcomes for infants experiencing this rare complication.
- Further research is warranted to validate this therapeutic strategy in a larger cohort.
Abstract:
Chylothorax is a rare complication following cavo-pulmonary connection and can lead to significant morbidity in infants and young children. We report here the case of a 3-month-old infant who underwent bilateral cavo-pulmonary connections, and developed severe chylothorax refractory to the usual conservative and surgical treatments. His chylothorax resolved after using a combination of parenteral octreotide (Sandostatin, Novartis Pharmaceuticals, East Hanover, NJ) and low-fat breast milk.

