Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Parkinson's disease.

Ali Samii1, John G Nutt, Bruce R Ransom

  • 1Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA. asamii@u.washington.edu

Lancet (London, England)
|June 3, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An updated definition of freezing of gait.

Nature reviews. Neurology·2026
Same author

Microvascular Decompression in a Patient With Positional Hemifacial Spasm: Case Report.

Neurosurgery practice·2025
Same author

Effects of Levodopa on Gait in People With Parkinson's Disease With and Without a History of Falls.

Movement disorders clinical practice·2025
Same author

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze.

Journal of visualized experiments : JoVE·2025
Same author

The Concept of Neuroglia - the State of the Art Circa 1900.

Glia·2025
Same author

Stride width and postural stability in frontal gait disorders and Parkinson's disease.

Journal of neurology·2024
Same journal

Assisted dying and the silencing of medicine's next generation.

Lancet (London, England)·2026
Same journal

Linguistic pragmatism: a woman with progressive abdominal pain in Thailand.

Lancet (London, England)·2026
Same journal

Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

Lancet (London, England)·2026
Same journal

[<sup>177</sup>Lu]Lu-edotreotide versus everolimus for gastroenteropancreatic neuroendocrine tumours (COMPETE): a phase 3, multicentre, randomised, open-label, superiority trial.

Lancet (London, England)·2026
Same journal

Research priorities for characterising Bundibugyo virus.

Lancet (London, England)·2026
Same journal

Rethinking treatment sequence in advanced gastroenteropancreatic neuroendocrine tumours.

Lancet (London, England)·2026
See all related articles

Parkinson's disease, a common movement disorder, results from neuron loss in the substantia nigra. Current treatments include drugs and surgery, with ongoing research into its enigmatic causes.

Area of Science:

  • Neurology
  • Neuroscience
  • Movement Disorders

Background:

  • Parkinson's disease (PD) is a prevalent neurodegenerative disorder affecting approximately 1% of adults over 60.
  • The condition is characterized by the selective loss of dopaminergic neurons in the substantia nigra.
  • The etiology of Parkinson's disease remains largely unknown in most cases.

Purpose of the Study:

  • To provide a comprehensive overview of Parkinson's disease for general medical practitioners.
  • To cover essential aspects including terminology, diagnosis, treatment, and pathogenesis.
  • To enhance understanding of this common movement disorder.

Main Methods:

  • This seminar synthesizes current knowledge on Parkinson's disease.
  • It reviews established diagnostic criteria and therapeutic approaches.

Related Experiment Videos

  • Pathogenesis is discussed based on existing scientific literature.

    • Main Results:

    • Parkinson's disease is a significant global health concern.
    • Therapeutic interventions, including pharmacological and surgical options, offer symptomatic relief.
    • Understanding the basics of PD is crucial for effective patient management.

    Conclusions:

    • Generalists require a foundational knowledge of Parkinson's disease for effective patient care.
    • Advances in treatment necessitate an updated understanding of diagnosis and management strategies.
    • Further research into the pathogenesis of Parkinson's disease is essential.