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Relationship between MMR vaccine and autism
Kristin C Klein1, Emily B Diehl
1Clinical Sciences Department, College of Pharmacy Services, University of Michigan Health System, Ann Arbor, MI 48109-0221, USA. kriklein@umich.edu
The Annals of Pharmacotherapy
|June 3, 2004
Summary
The measles, mumps, and rubella (MMR) vaccine is not linked to autism. Extensive literature review found no scientific evidence to support a connection between MMR vaccination and autism development.
Area of Science:
- Immunology
- Neurodevelopmental Disorders
- Vaccine Safety
Background:
- The measles, mumps, and rubella (MMR) vaccine is a common childhood immunization.
- Concerns have been raised regarding a potential link between the MMR vaccine and autism spectrum disorder.
Purpose of the Study:
- To critically evaluate the scientific literature for evidence supporting a relationship between MMR vaccination and autism.
Main Methods:
- A comprehensive literature search was performed using MEDLINE.
- Keywords included measles, mumps, rubella, and autism.
- References from identified articles were also reviewed.
Main Results:
- Ten studies specifically investigating the MMR vaccine-autism link were identified.
- Exclusion criteria focused on relevant studies, omitting review articles and commentaries.
Conclusions:
- Current scientific literature does not support a causal relationship between the MMR vaccine and the development of autism.
- The available evidence indicates no association between receiving the MMR vaccine and autism.