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Related Experiment Videos

Unintentional intravenous infusion of Golytely in a 4-year-old girl.

Wilfredo Rivera1, Larissa I Velez, Daniel D Guzman

  • 1University of Texas Southwestern (UTSW) Emergency Medicine/Section of Toxicology, Dallas, TX 75390-8579, USA. wilfredo.rivera@utsouthwestern.edu

The Annals of Pharmacotherapy
|June 3, 2004
PubMed
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An accidental intravenous infusion of Golytely (polyethylene glycol and electrolyte solution) in a child did not cause systemic toxicity. This case highlights the importance of careful medication administration to prevent adverse events in pediatric patients.

Area of Science:

  • Toxicology
  • Pediatric Emergency Medicine
  • Clinical Case Reports

Background:

  • Polyethylene glycol and electrolyte solution (PEG-ELS), commonly known as Golytely, is used for gastrointestinal decontamination via nasogastric tube.
  • Intravenous administration of PEG-ELS is not indicated and carries potential risks.
  • Accidental intravenous administration of PEG-ELS has not been previously documented in pediatric cases.

Observation:

  • A 4-year-old girl ingested a significant amount of 6-mercaptopurine and received activated charcoal.
  • Golytely was ordered via nasogastric tube but was inadvertently administered intravenously.
  • The patient remained hemodynamically stable with no signs of acidosis, renal failure, or ethylene glycol toxicity.

Findings:

  • Despite the incorrect route of administration, the pediatric patient experienced no systemic toxicity from the intravenous Golytely infusion.

Related Experiment Videos

  • Monitoring of acid-base status, renal function, and pulmonary function is crucial in cases of accidental PEG-ELS intravenous infusion.
  • This event underscores the potential for medication errors in clinical settings.

    • Implications:

    • Healthcare protocols must be strengthened to prevent medication administration errors, particularly with solutions like PEG-ELS.
    • This case suggests that PEG-ELS may have a wider safety margin than previously assumed for intravenous administration in specific pediatric scenarios.
    • Further vigilance and adherence to established administration guidelines are essential for patient safety in toxicology and emergency medicine.