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The use of in-line intravenous filters in sick newborn infants

R A van Lingen1, W Baerts, A C M Marquering

  • 1Department of Paediatrics Princess Amalia, Isala Clinics, Zwolle, The Netherlands. r.a.van.lingen@isala.nl

Acta Paediatrica (Oslo, Norway : 1992)
|June 4, 2004
PubMed

Insights

Using an in-line filter in intravenous fluid therapy significantly reduced major complications like sepsis and thrombi in newborn infants. This method also offers substantial cost savings by decreasing the need for daily intravenous line changes.

Area of Science:

  • Neonatal care
  • Pediatric medicine
  • Medical device technology

Background:

  • Intravenous fluid therapy is essential for newborn infants.
  • Major complications can arise from intravenous fluid administration.
  • Current practices involve frequent changes of intravenous lines, incurring costs.

Purpose of the Study:

  • To assess the impact of in-line filters on reducing major complications in neonatal intravenous therapy.
  • To evaluate the economic benefits of using in-line filters compared to daily intravenous line changes.

Main Methods:

  • A prospective controlled study involving 88 infants.
  • Infants were randomly assigned to receive filtered or non-filtered infusions via a central catheter.
  • Key outcomes measured included bacteremia, phlebitis, thrombosis, sepsis, and associated costs.

Main Results:

  • Significant reductions in thrombi and clinical sepsis were observed in the filter group compared to the control group (p < 0.05).
  • Bacterial contamination rate on the upstream surface of filters was 14%.
  • Mean disposable costs decreased from 31.17 euros to 23.79 euros in the filter group.

Conclusions:

  • In-line filters significantly decrease major complications in neonatal intravenous therapy.
  • The use of in-line filters results in substantial cost savings.
  • This intervention offers a dual benefit of improved patient outcomes and economic efficiency.
Abstract

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