Microarray analysis and functional characterization of the nitrosative stress response in nonmucoid and mucoid
Aaron M Firoved1, Simon R Wood, Wojciech Ornatowski
1College of Pharmacy, Toxicology Program, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Journal of Bacteriology
|June 4, 2004
Abstract:
The type strain of Pseudomonas aeruginosa, PAO1, showed great upregulation of many nitrosative defense genes upon treatment with S-nitrosoglutathione, while the mucoid strain PAO578II showed no further upregulation above its constitutive upregulation of nor and fhp. NO* consumption however, showed that both strains mount functional, protein synthesis-dependent NO*-consumptive responses.


