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Jaundice in pregnancy: a clinical study
C S Sarkar1, A K Giri, T K Maity
1Department of Obstetrics and Gynaecology, Nilratan Sircar Medical College and Hospital, Calcutta.
Journal of the Indian Medical Association
|May 1, 1992
Summary
Jaundice in pregnancy affects 1 in 429 women, often occurring in the third trimester. Viral hepatitis is the most common cause, leading to significant maternal and perinatal mortality risks.
Area of Science:
- Obstetrics and Gynecology
- Hepatology
- Maternal-Fetal Medicine
Background:
- Jaundice during pregnancy is a rare but serious condition.
- Understanding its incidence, risk factors, and outcomes is crucial for maternal and fetal health.
Purpose of the Study:
- To determine the incidence of jaundice in pregnancy.
- To identify demographic, clinical, and etiological characteristics of jaundice in pregnant women.
- To evaluate maternal and perinatal mortality associated with jaundice in pregnancy.
Main Methods:
- Retrospective study analyzing cases of jaundice in pregnant women.
- Data collected on patient demographics, clinical presentation, jaundice severity (serum bilirubin), anemia, booking status, trimester of presentation, jaundice-delivery interval, etiology, and outcomes.
Main Results:
- Incidence of jaundice in pregnancy was 1 in 429.
- Most affected were primigravida, aged 20-30 years (70%), and unbooked (60%).
- Severe jaundice (25%) and anemia (70%) were common; 80% of cases were due to viral hepatitis.
- Cases predominantly occurred in the third trimester with a jaundice-delivery interval >4 weeks in 60%.
Conclusions:
- Jaundice in pregnancy presents significant risks, with high rates of severe jaundice, anemia, and a strong association with viral hepatitis.
- Maternal mortality was 1 in 20, and perinatal mortality was 41%, highlighting the critical need for timely diagnosis and management.