Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Vaccines pharmacovigilance].

Elisabeth Autret-Leca1, Annie-Pierre Jonville-Béra, Frédérique Beau-Salinas

  • 1Service de pharmacologie clinique et Centre regional de pharmacovigilance et d'informations sur le médicament, CHRU, 37044 Tours. autret-leca@med.univ-tours.fr

La Revue Du Praticien
|June 5, 2004
PubMed
Summary

Vaccine pharmacovigilance monitors rare side effects in healthy individuals. Post-marketing surveillance is crucial for identifying and evaluating real-world vaccination risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Angioedema reported with tissue plasminogen activators: A need to communicate on bradykinin- and histamine-mediated mechanisms.

Therapie·2026
Same author

Pregnancy and neonatal outcome following in utero exposure to CFTR modulators: A multicentre prospective case series.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2025
Same author

The safety profile of fluoroquinolones.

Infectious diseases now·2025
Same author

[Deleterious impact of a non-steroidal anti-inflammatory taken for fever or acute pain in case of streptococcal infection].

Therapie·2025
Same author

Intravitreal vascular endothelial growth factor inhibitors and cardiovascular adverse drug reactions: Added value of the data of the French pharmacovigilance spontaneous reporting assessment.

Therapie·2025
Same author

Thrombotic Microangiopathy From Peptide Receptor Radionuclide Therapy.

Kidney international reports·2025

Area of Science:

  • Pharmacovigilance
  • Vaccine safety
  • Drug monitoring

Context:

  • Vaccines target healthy populations, presenting unique safety considerations.
  • Adverse events can be antigen-specific (e.g., post-MMR meningitis) or component-related (e.g., aluminum-associated myofasciitis).
  • Standardized pharmacovigilance procedures, including spontaneous reporting and pharmaco-epidemiological studies, are employed.

Purpose:

  • To identify and manage vaccine-related undesirable effects.
  • To evaluate the real-world risks associated with vaccine administration.
  • To ensure the ongoing safety and efficacy of vaccines.

Summary:

  • Pharmaco-epidemiological studies have investigated specific vaccine-adverse event associations.
  • Studies have examined reactions to Haemophilus b vaccines, excluded links to sudden infant death, and assessed risks for demyelination or autoimmune diseases with hepatitis B vaccines.
  • Evidence does not support associations between MMR vaccination and Crohn's disease or autism.

Impact:

  • Identifies frequently encountered side effects during vaccine commercialization.
  • Post-marketing surveillance detects rare and serious adverse events.
  • Intensive and systematic surveillance is essential for evaluating actual vaccination risks.

Related Experiment Videos