Related Experiment Video
Updated: Aug 24, 2026
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
Silicone oil content in ophthalmic viscosurgical devices
Arne Ohrstrom1, Bengt Svensson, Susan Tegenfeldt
1Department of Ophthalmology, Central Hospital, Vasteras 72189, Sweden. arne.ohrstrom@itvastmanland.se
Purpose:
To examine the silicone oil content in 5 brands of ophthalmic viscoelastic devices (OVDs).
Setting:
Department of Ophthalmology, Central Hospital of Vasteras, Vasteras, Sweden.
Methods:
Phacoemulsification with intraocular lens (IOL) implantation was performed in 250 patients. Five brands of OVD were used, each one in 50 procedures. From each brand, 5 separate batches, each consisting of 10 syringes, were used. The 250 samples from identical batches were sent for spectrophotometric analysis, and 250 samples were used during surgery.
Results:
The silicone oil content varied significantly between the OVD brands.
Conclusions:
Silicone oil is a common contaminant in many OVDs. Ophthalmic viscosurgical devices with relatively low silicone oil content are available.
