Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Single-piece AcrySof in the newborn rabbit eye.

Maria Kugelberg1, Kayvan Shafiei, Charlotta Zetterström

  • 1St. Erik's Eye Hospital, 112 82 Stockholm, Sweden. mkugelberg@sankterik.se

Journal of Cataract and Refractive Surgery
|June 5, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ten-year trends of delayed sequential bilateral cataract surgery (DSBCS) in Sweden: a register-based study.

Eye and vision (London, England)·2024
Same author

[2.6 million cataract surgeries: 31 years with the Swedish National Cataract Register 1992-2022].

Lakartidningen·2024
Same author

Two point four million cataract surgeries: 30 years with the Swedish National Cataract Register, 1992-2021.

Journal of cataract and refractive surgery·2023
Same author

Ten-year trends of immediate sequential bilateral cataract surgery (ISBCS) as reflected in the Swedish National Cataract Register.

Acta ophthalmologica·2023
Same author

Self-assessed visual function outcome in cataract surgery: minimum important difference of the Catquest-9SF questionnaire.

Eye and vision (London, England)·2022
Same author

Analysis of age at detection and outcomes of dense unilateral congenital cataract surgery for children on the paediatric cataract register.

Acta paediatrica (Oslo, Norway : 1992)·2022
Same journal

Light adjustable lens implantation with cataract surgery in eyes with macular pathology.

Journal of cataract and refractive surgery·2026
Same journal

Comment on: Use of intracameral antibiotics prophylaxis in patients with posterior capsule rupture during cataract surgery: systemic review and meta-analysis.

Journal of cataract and refractive surgery·2026
Same journal

Dehydration and Rehydration Behavior of Ultra-High-Fluence Extracorporeal Cross-Linked Corneal Allogenic Intrastromal Ring Segments (ECO-CAIRS).

Journal of cataract and refractive surgery·2026
Same journal

Multimodal Deep Learning for Predicting Postoperative Vault and Selecting ICL Sizes Using AS-OCT and UBM Images.

Journal of cataract and refractive surgery·2026
Same journal

Reply: Evaluating large language models vs residents in cataract and refractive surgery: comparative analysis using the American Academy of Ophthalmology Self-Assessment Program.

Journal of cataract and refractive surgery·2026
Same journal

Comment on: Evaluating large language models vs residents in cataract and refractive surgery: comparative analysis using the American Academy of Ophthalmology Self-Assessment Program.

Journal of cataract and refractive surgery·2026
See all related articles

The single-piece AcrySof SA30AT intraocular lens (IOL) in newborn rabbits showed fewer complications like secondary glaucoma compared to aphakic eyes. Careful implantation is crucial for optimal outcomes in pediatric eyes.

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Veterinary Medicine

Background:

  • Intraocular lens (IOL) technology is advancing for pediatric eye care.
  • Understanding the behavior of new IOLs in developing eyes is critical.
  • The AcrySof SA30AT is a single-piece acrylic IOL with potential applications in pediatric populations.

Purpose of the Study:

  • To assess the performance and postoperative complications of the single-piece AcrySof SA30AT IOL in newborn rabbit eyes.
  • To compare outcomes in pseudophakic (IOL-implanted) versus aphakic (IOL-absent) eyes.
  • To evaluate the impact of the IOL on ocular growth and secondary glaucoma development.

Main Methods:

  • Clear lens extraction followed by single-piece AcrySof SA30AT IOL implantation in one eye of 20 newborn rabbits.

Related Experiment Videos

  • Preoperative and 1- and 2-month postoperative measurements included axial length and corneal diameter.
  • Clinical examinations assessed IOL position and secondary glaucoma; histological evaluation and after-cataract wet mass measurements were performed post-mortem.

    • Main Results:

    • Pseudophakic eyes showed no secondary glaucoma, unlike aphakic eyes (3/20 rabbits).
    • Aphakic eyes exhibited more posterior synechias and smaller pupil size.
    • After-cataract formation was significantly greater in aphakic eyes; no significant difference in inflammation was observed histologically.

    Conclusions:

    • The AcrySof SA30AT IOL appears to induce minimal inflammation and may inhibit secondary glaucoma in this model.
    • The IOL did not significantly retard eye growth compared to previously tested IOLs.
    • Ensuring complete capsulorhexis coverage of the IOL optic is vital, particularly in small pediatric eyes.