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BioPD: a web-based information center for bioactive peptides.

Lei Shi1, Qipeng Zhang, Wei Rui

  • 1Institute of Cardiovascular Science, Peking University Health Science Center, Xueyuan Road 38, Beijing 100083, PR China. shilei@bjmu.edu.cn

Regulatory Peptides
|June 5, 2004
PubMed
Summary

The Bioactive Peptide Database (BioPD) is a comprehensive resource detailing over 1100 bioactive peptides from humans, mice, and rats. It integrates protein and gene sequences, interactions, and disease data, serving as a key information hub.

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Area of Science:

  • Biochemistry
  • Bioinformatics
  • Genomics

Background:

  • Bioactive peptides play crucial roles in physiological processes.
  • Existing resources may lack comprehensive integration of peptide-related data.
  • A centralized database is needed for efficient exploration of bioactive peptides.

Purpose of the Study:

  • To develop and present the Bioactive Peptide Database (BioPD).
  • To provide a comprehensive, web-based resource for bioactive peptides.
  • To facilitate research on bioactive peptides by integrating diverse data types.

Main Methods:

  • Compilation of over 1100 protein sequences from human, mouse, and rat.
  • Integration of gene sequences, protein interactions, and disease data.

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  • Development of a searchable interface with links to external databases (PDB, InterPro, Pfam, OMIM).
  • Main Results:

    • BioPD contains extensive data on 1100+ bioactive peptides.
    • The database includes protein and gene sequences, annotations, interactions, and disease associations.
    • Multiple search functionalities and cross-references enhance data accessibility.

    Conclusions:

    • BioPD serves as a valuable information center for bioactive peptides.
    • The database acts as a gateway for exploring bioactive peptide functions and roles.
    • BioPD supports research in various fields, including medicine and biology.