Related Experiment Video
Updated: Aug 24, 2026

Preparation of Cross-Linked Sodium Alginate Microspheres with Different Metal Ions Using the Microfluidic Electrospray Technology
Published on: June 7, 2024
Interaction between alginates and manganese cations: identification of preferred cation binding sites
N Emmerichs1, J Wingender, H-C Flemming
1Institut für Chemie, Universität Duisburg-Essen, 47057 Duisburg, Germany.
Abstract:
Algal and bacterial alginates have been studied by means of 13C NMR spectroscopy in presence of paramagnetic manganese ions in order to reveal the nature of their interaction with bivalent cations. It is found that the mannuronate blocks bind manganese cations externally near their carboxylate groups, while guluronate blocks show the capability to integrate Mn2+ into pocket-like structures formed by adjacent guluronate residues. In alternating mannuronate-guluronate blocks, manganese ions preferentially locate in a concave structure formed by guluronate-mannuronate pairs. Partial acetylation of the alginate generally reduces its capability to interact with bivalent cations, however, the selectivity of the binding geometry is conserved. The results may serve as a hint for the better understanding of the alginate gelation in presence of calcium ions.
More Related Videos
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
09:27Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
Published on: April 22, 2016
Related Concept Videos
Extraction: Advanced Methods
Ligand Binding and Linkage
Qualitative Analysis
For instance, group IV...
Radical Oxidation of Allylic and Benzylic Alcohols
Complexometric Titration: Ligands
Complexation Equilibria: The Chelate Effect