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Updated: Aug 24, 2026

07:20
Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
cis-Diphenylbis(1,3,5-triaza-7-phosphaadamantane-kappaP)platinum(II)
1Department of Chemistry and Biochemistry, Rand Afrikaans University, Auckland Park, Johannesburg, South Africa 2006.
Abstract:
The structure of the title compound, [Pt(C(6)H(5))(2)(C(6)H(12)N(3)P)(2)] or [Pt(Ph)(2)(PTA)(2)] (where Ph is phenyl and PTA is 1,3,5-triaza-7-phosphaadamantane), is discussed. Selected geometric parameters are: Pt-P = 2.2888 (16) and 2.2944 (17) A, Pt-C = 2.052 (5) and 2.064 (6) A, C-Pt-C = 84.6 (2) degrees and P-Pt-P = 99.28 (6) degrees. The effective cone angle for the PTA ligands was calculated as 113 degrees.

