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Updated: Aug 10, 2026
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Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
Idiopathic intracranial hypertension
Deborah I Friedman1, Daniel M Jacobson
1Departments of Ophthalmology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA. Deborah_Friedman@urmc.rochester.edu
Summary
Idiopathic intracranial hypertension, a condition with unknown causes, has seen significant advancements in diagnosis and treatment over the last 20 years, improving patient care.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by increased pressure within the skull without a clear structural or fluid cause.
- First described over a century ago, the exact pathogenesis of IIH remains elusive.
Purpose of the Study:
- To review the historical context and recent advancements in the management of idiopathic intracranial hypertension.
- To highlight progress in diagnostic and therapeutic strategies for IIH patients.
Main Methods:
- Literature review of historical and contemporary studies on idiopathic intracranial hypertension.
- Analysis of diagnostic criteria and therapeutic interventions developed over the past two decades.
Main Results:
- Despite unknown pathogenesis, significant progress has been made in managing IIH.
- Recent developments have substantially improved diagnostic accuracy and therapeutic efficacy for patients.
Conclusions:
- Idiopathic intracranial hypertension management has advanced considerably, offering better outcomes for patients.
- Continued research into pathogenesis may further refine diagnostic and therapeutic approaches.
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