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Factor V Leiden mutation in pregnancy.

Susan Murphy Cohen

    Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN
    |June 8, 2004
    PubMed
    Summary
    This summary is machine-generated.

    Pregnancy increases clot risk, especially with inherited thrombophilias like Factor V Leiden mutation. Nurses need knowledge for screening, counseling, and managing affected pregnant patients on anticoagulant therapy.

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    Area of Science:

    • Obstetrics and Gynecology
    • Hematology
    • Nursing Education

    Background:

    • Pregnancy naturally elevates thrombus formation risk.
    • Inherited thrombophilias exacerbate risks of deep venous thrombosis and adverse pregnancy outcomes.
    • Factor V Leiden mutation is the most prevalent inherited thrombophilia.

    Purpose of the Study:

    • To highlight the importance of Factor V Leiden mutation knowledge for nurses.
    • To emphasize the need for informed screening, diagnosis, and risk management.
    • To outline essential nursing care and implications of anticoagulant therapy in pregnant patients.

    Main Methods:

    • Review of current literature on thrombophilia in pregnancy.
    • Analysis of Factor V Leiden mutation prevalence in different populations.

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  • Discussion of nursing responsibilities in managing affected patients.

    • Main Results:

    • Factor V Leiden mutation affects approximately 5% of White and 1% of Black populations.
    • Knowledge gaps in nursing care for Factor V Leiden mutation can impact patient outcomes.
    • Anticoagulant therapy during pregnancy requires careful consideration and management.

    Conclusions:

    • Nurses require comprehensive education on Factor V Leiden mutation.
    • Proactive screening and risk reduction counseling are crucial.
    • Effective management of pregnant patients with thrombophilia improves perinatal outcomes.