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Hodgkin's disease: Kuwait experience.

Salem H Al-Shemmari1, Salah Al-Humood, Reem Ameen

  • 1Department of Medicine, Faculty of Medicine, PO Box 24923, Kuwait University, Safat, Kuwait. salemalshemmari@hotmail.com

Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre
|June 8, 2004
PubMed
Summary

This study describes Hodgkin

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Area of Science:

  • Hematology
  • Oncology
  • Epidemiology

Background:

  • Hodgkin's lymphoma is a significant hematologic malignancy.
  • Understanding its characteristics in specific populations is crucial for targeted treatment.

Purpose of the Study:

  • To detail the histologic subtypes, clinical presentation, and treatment outcomes of Hodgkin's lymphoma in Kuwait.
  • To analyze patient demographics and disease characteristics within the Kuwaiti population.

Main Methods:

  • Retrospective analysis of 137 patients diagnosed between 1980 and 1998.
  • Data collection included demographics, histology, clinical presentation, stage, extranodal involvement, and treatment modality.
  • Histology reports were reviewed from hospital records.

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Main Results:

  • Nodular sclerosis (46.4%) and mixed cellularity (30%) were dominant subtypes.
  • Most cases (64%) presented at advanced stages, with common extranodal involvement in the liver and gastrointestinal tract.
  • Disease-free survival rates varied by treatment: radiotherapy alone (100%), chemotherapy alone (88%), and combined modality (65%), with an overall 5-year disease-free survival of 84%.

Conclusions:

  • Combined radiotherapy and chemotherapy demonstrated a remarkable outcome in this cohort.
  • Further evaluation of long-term treatment complications is warranted.