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Malignant rhabdoid tumour of the brain

J M Abdullah1, Z A A Rahman, A R M Ariff

  • 1Department of Neuroscience, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. unitneurosainsppspusm@yahoo.com

Singapore Medical Journal
|June 8, 2004
PubMed

Insights

Rhabdoid tumors are aggressive childhood brain cancers with a poor outlook. This case highlights a fatal outcome in a 13-month-old girl despite surgical interventions.

Area of Science:

  • Pediatric Oncology
  • Neuro-oncology
  • Pathology

Background:

  • Rhabdoid tumors are rare, aggressive neoplasms predominantly affecting young children.
  • These tumors, particularly those in the central nervous system, are associated with a dismal prognosis.

Observation:

  • A 13-month-old Malay female presented with a large, irregular enhancing mass in the left fronto-temporo-parietal brain region.
  • Computed tomography revealed obstructive hydrocephalus secondary to the intracranial tumor.

Findings:

  • The rhabdoid tumor demonstrated resistance to treatment, with no size reduction after three surgical resections.
  • The patient's clinical course was rapidly progressive, leading to death four months post-diagnosis.

Implications:

  • This case underscores the aggressive nature and limited therapeutic options for pediatric rhabdoid brain tumors.
  • Further research into novel therapeutic strategies is crucial for improving outcomes in affected children.

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