Otitis caused by Scedosporium apiospermum in an immunocompetent child

H S Bhally1, C Shields, S Y Lin

  • 1Division of Microbiology, Johns Hopkins University School of Medicine, USA. hbhally@hotmail.com

Insights

Scedosporium apiospermum, a rare cause of ear infections, was successfully treated in an 8-year-old boy using surgery and antifungal medication. This case highlights a rare fungal pathogen in an immunocompetent host.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Scedosporium apiospermum (Pseudallescheria boydii) is a widespread mold.
  • It is an emerging pathogen, particularly in immunocompromised individuals.
  • Otomycosis caused by S. apiospermum is exceptionally rare.

Observation:

  • An 8-year-old immunocompetent male presented with otitis media and otitis externa.
  • The infection was diagnosed as Scedosporium apiospermum.

Findings:

  • The patient received a combination of surgical debridement and topical clotrimazole.
  • This treatment regimen resulted in a successful recovery.
  • The case represents a rare instance of S. apiospermum causing otologic infections in an immunocompetent host.

Implications:

  • This case expands the known clinical spectrum of S. apiospermum infections.
  • It underscores the importance of considering fungal etiologies even in immunocompetent patients with otologic complaints.
  • The successful treatment highlights effective therapeutic options for this rare condition.

Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...