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Confocal Imaging of Double-Stranded RNA and Pattern Recognition Receptors in Negative-Sense RNA Virus Infection
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Published on: January 26, 2019

Langerhans cells exhibit low responsiveness to double-stranded RNA

Hideki Fujita1, Akihiko Asahina, Hiroshi Mitsui

  • 1Department of Dermatology, University of Tokyo Graduate School of Medicine, Japan.

Biochemical and Biophysical Research Communications
|June 9, 2004
PubMed
Summary

Langerhans cells (LC) show low responsiveness to double-stranded RNA (dsRNA), unlike splenic dendritic cells (DC). Keratinocytes (KC) may initiate skin antiviral responses through IL-1alpha production, promoting LC maturation.

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