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Published on: December 14, 2019
Frey procedure for surgical management of chronic pancreatitis in children
Michael D Rollins1, Rebecka L Meyers
1Division of Pediatric Surgery, Primary Children's Medical Center, Salt Lake City, UT 84113, USA.
Insights
The Frey procedure offers effective surgical management for pediatric chronic pancreatitis, particularly when conservative treatments fail. This approach helps prevent recurrent pancreatic head disease in children.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Pancreatic Diseases
Background:
- Chronic pancreatitis management in children presents unique challenges.
- The Frey procedure was adopted due to recurrent disease post-longitudinal pancreaticojejunostomy (LPJ).
- This study details the first use of the Frey procedure in pediatric patients.
Purpose of the Study:
- To evaluate the efficacy of the Frey procedure in managing pediatric chronic pancreatitis.
- To assess the Frey procedure's role in preventing recurrent disease in the pancreatic head.
- To compare outcomes between LPJ and Frey procedures in children.
Main Methods:
- Retrospective chart review of pediatric patients undergoing drainage or resection for chronic pancreatitis (1995-2002).
- Analysis of patients who underwent either LPJ (3) or Frey (8) procedures.
- Assessment of clinical outcomes and follow-up data.
Main Results:
- Eleven children (ages 8-18) were treated with LPJ or Frey procedures.
- Diverse etiologies included idiopathic, familial, and congenital anomalies.
- Eight of eleven patients achieved excellent or good outcomes post-surgery, with an average follow-up of 4.6 years.
Conclusions:
- The Frey procedure is a viable and effective option for pediatric chronic pancreatitis unresponsive to conservative care.
- It demonstrates potential in preventing recurrent pancreatic head disease in children.
- Surgical intervention, including the Frey procedure, can yield positive outcomes in pediatric chronic pancreatitis.
Background:
The authors adopted the Frey procedure for the surgical management of chronic pancreatitis after one of their patients had recurrent disease in the head of the gland after a longitudinal pancreaticojejunostomy (LPJ or modified Puestow procedure). This is the first description of its use in children.
Methods:
A retrospective chart review was performed of all children undergoing a drainage or resection procedure for chronic pancreatitis from 1995 to 2002.
Results:
Eleven children (6 boys, 5 girls, ages 8 to 18 years) underwent either the LPJ (3) or Frey (8) procedure. Etiologies included: idiopathic (5), familial (2), congenital anomaly of the major papilla (1), pancreatic head mass (1), short bowel syndrome (1), and pancreatic divisum (1). Before surgical therapy, patients had been symptomatic 2.3 years (range, 1 month to 6 years) and had been hospitalized for pancreatitis 4 times (range, 1 to 10). Four patients did not respond to endoscopic stenting, and 5 had a pancreatic pseudocyst. Patients were followed up in clinic an average of 2.5 years, with total time elapsed since surgery averaging 4.6 years. Eight of 11 patients experienced excellent or good results subsequent to surgical intervention.
Conclusions:
The Frey procedure is effective for children who have not responded to conservative management of chronic pancreatitis and may prevent recurrent disease in the head of the gland.
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