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Penile involvement with hand-foot syndrome
1Oncology Department, Marshfield Clinic-Wausau Center, Wausau, Wisconsin 54401, USA.
American Journal of Clinical Dermatology
|June 10, 2004
Summary
Hand-foot syndrome, a chemotherapy side effect, usually affects palms and soles. This case study details the first instance of penile involvement alongside typical hand-foot syndrome symptoms.
Area of Science:
- Oncology
- Dermatology
- Clinical Case Reports
Background:
- Hand-foot syndrome, also known as palmar plantar erythrodysesthesia, is a common chemotherapy-induced skin reaction.
- It typically manifests as painful redness and peeling on the palms and soles.
Observation:
- This report describes a unique case of hand-foot syndrome.
- The patient presented with classic symptoms on the hands and soles.
- Additionally, the patient experienced penile erythema, pain, and desquamation.
Findings:
- This is the first documented case of hand-foot syndrome involving the penis.
- The findings expand the known clinical presentation of this chemotherapy side effect.
Implications:
- This case highlights the need for broader clinical awareness of hand-foot syndrome presentations.
- It suggests that chemotherapy-induced skin reactions may manifest in unexpected anatomical locations.
- Further research may be warranted to understand the mechanisms and management of atypical hand-foot syndrome.