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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Related Experiment Video

Updated: Apr 14, 2026

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

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Irritable bowel syndrome and surgery: a multivariable analysis.

George F Longstreth1, Janis F Yao

  • 1Department of Gastroenterology, Kaiser Permanente Medical Care Plan, Kaiser Medical Center, 4647 Zion Avenue, San Diego, CA 92120, USA. George.F.Longstreth@kp.org

Gastroenterology
|June 10, 2004
PubMed
Summary
This summary is machine-generated.

Patients with irritable bowel syndrome (IBS) undergo significantly higher rates of surgery, including cholecystectomy, appendectomy, hysterectomy, and back surgery. This study highlights a strong independent association between IBS and these surgical procedures.

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Area of Science:

  • Gastroenterology
  • Surgical Epidemiology
  • Public Health

Background:

  • Irritable bowel syndrome (IBS) is prevalent, and patients often have high surgical intervention rates.
  • Understanding factors associated with surgery in IBS patients is crucial for healthcare management.

Purpose of the Study:

  • To investigate demographic and medical factors linked to surgical histories in health examinees.
  • To determine if Irritable Bowel Syndrome (IBS) is independently associated with specific surgical procedures.

Main Methods:

  • A large-scale analysis of 89,008 health examinees using self-completed questionnaires.
  • Logistic regression analysis was employed to assess associations between IBS and six types of surgeries.
  • Validation of physician-diagnosed IBS and surgical history was performed on a subset of participants.

Main Results:

  • Irritable Bowel Syndrome (IBS) was reported by 5.2% of examinees, with higher prevalence in women (7.5%) than men (3.0%).
  • IBS patients showed significantly higher rates for cholecystectomy (12.4% vs 4.1%), appendectomy (21.1% vs 11.7%), hysterectomy (33.2% vs 17.0%), and back surgery (4.4% vs 2.9%).
  • Adjusted analyses confirmed IBS was independently associated with cholecystectomy (OR 2.09), appendectomy (OR 1.45), hysterectomy (OR 1.70), and back surgery (OR 1.22).

Conclusions:

  • Physician-diagnosed Irritable Bowel Syndrome (IBS) is significantly associated with increased rates of cholecystectomy, appendectomy, hysterectomy, and back surgery.
  • These findings underscore the substantial surgical burden in patients with IBS.
  • IBS should be considered a relevant factor when evaluating surgical risk and patient history.