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Structure-activity relationship studies of CNS agents. Part 4:
J Boksa1, S Misztal, E Chojnacka-Wójcik
1Institute of Pharmacology, Polish Academy of Sciences, Kraków.
Die Pharmazie
|April 1, 1992
Abstract:
Seven derivatives of 1,2,3,4-tetrahydro-beta-carbolin-1-one have been prepared. Three of them showed significant central anti-serotonin activity, comparable with that of trazodone or etoperidone. Some structural features were found to be important for the central antiserotonin activity of the investigated class of compounds.