Related Experiment Video
Updated: Jul 21, 2026
07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Neurological complications in eclampsia: a case series
Parikshit D Tank1, Anahita R Chauhan, Moudhulika S Bhattacharya
1Department of Obstetrics and Gynecology, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Parel, Mumbai, India.
International Journal of Fertility and Women'S Medicine
|June 11, 2004
Summary
Neurological abnormalities in eclampsia significantly impact maternal mortality. Early delivery and critical care are vital for managing these severe cases and improving outcomes.
Area of Science:
- Obstetrics and Gynecology
- Neurology
- Critical Care Medicine
Background:
- Neurological abnormalities are a significant cause of maternal mortality in eclampsia.
- Understanding the epidemiology and outcomes of eclampsia with neurological complications is crucial for improving patient care.
Purpose of the Study:
- To investigate the epidemiology, neurological, and obstetric outcomes of patients with eclampsia and neurological abnormalities.
- To identify factors contributing to cerebral pathology and evaluate management strategies.
Main Methods:
- Retrospective analysis of 19 eclampsia cases with neurological abnormalities at a referral center.
- Management included stabilization, early delivery, and magnesium sulfate as primary anticonvulsant.
- Computerized tomography (CT) scans were used for diagnosis.
Main Results:
- 19 out of 61 eclampsia cases (31.14%) presented with neurological abnormalities.
- Comatose patients had the highest mean arterial pressure (MAP).
- CT scans effectively diagnosed cerebrovascular accidents and cerebral edema; Phenytoin controlled seizures in 7/8 cases.
Conclusions:
- Critical care support is essential for managing neurological abnormalities in eclampsia.
- High MAP and thrombocytopenia may be linked to cerebral pathology.
- CT scans are effective diagnostic tools, and early delivery improves maternal outcomes.
Related Concept Videos
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:13Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
01:19Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
01:22Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
01:20Seizures l: Introduction
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
01:29Hepatic Encephalopathy
DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...