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IgA immunoassay for the diagnosis of bancroftian filariasis
S Chanteau1, J L Cartel, P M Martin
1Institut Territorial de Recherches Médicales Louis Malardé, Papeete Tahiti, French Polynesia.
Tropical Medicine and Parasitology : Official Organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft Fur Technische Zusammenarbeit (GTZ)
|June 1, 1992
Abstract:
In some parasitic infection such as toxoplasmosis, specific IgA is a highly reliable marker of active infection. In bancroftian filariasis, only 10 of 20 (50%) and 3 of 20 (15%) of the microfilaremic patients were positive for IgA anti-Brugia malayi using respectively indirect ELISA and immunocapture ELISA tests. As regard to these low sensitivities, the detection of specific IgA is unlikely to be a useful test for the diagnosis of active Wuchereria bancrofti infection.