Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Postoperative nausea and vomiting].

C C Apfel1, N Roewer

  • 1Department of Anesthesiology and Perioperative Medicine, Outcomes Research Institute, University of Louisville, KY 40202, USA. apfel@ponv.org

Der Anaesthesist
|June 12, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delphinidin modulates neuroinflammation and behavioral deficits in a Parkinson's disease mouse model.

NPJ Parkinson's disease·2026
Same author

[Identification of the epidural space using pressure waveform analysis (CompuFlo® technology): a case series].

Der Anaesthesist·2019
Same author

Structured analysis, evaluation and report of the emergency response to a terrorist attack in Wuerzburg, Germany using a new template of standardised quality indicators.

Scandinavian journal of trauma, resuscitation and emergency medicine·2018
Same author

[Quality indicators for rescue operations in terrorist attacks or other threats : A pilot study after the Würzburg terrorist attack of July 2016].

Der Anaesthesist·2017
Same author

Body posture during simulated tracheal intubation: GlideScope(®) videolaryngoscopy vs Macintosh direct laryngoscopy for novices and experts.

Anaesthesia·2015
Same author

[Venoarterial extracorporeal membrane oxygenation for out-of-hospital cardiac arrest. Case series of prehospital and in-hospital therapies].

Der Anaesthesist·2015
Same journal

[Promoting young academics in anesthesiology: factors for an attractive internship].

Der Anaesthesist·2022
Same journal

[Respiratory support in COVID-19: all in due time!]

Der Anaesthesist·2022
Same journal

[Noninvasive respiratory support and invasive ventilation in COVID‑19 : Where do we stand today?]

Der Anaesthesist·2022
Same journal

[Management of acutely decompensated liver cirrhosis in emergency and critical care medicine].

Der Anaesthesist·2022
Same journal

[Anesthesia in patients with acute porphyria].

Der Anaesthesist·2022
Same journal

[Quality and safe anesthesia for all children : That is their right!]

Der Anaesthesist·2022
See all related articles

Identifying patient risk factors is key to preventing postoperative nausea and vomiting (PONV). A tailored antiemetic strategy based on risk level, rather than a one-size-fits-all approach, improves PONV management.

Area of Science:

  • Anesthesiology
  • Pharmacology
  • Clinical Medicine

Context:

  • Postoperative nausea and vomiting (PONV) is a common complication with multifactorial causes.
  • While several mechanisms contribute to PONV, their precise roles remain unclear.
  • Key etiological factors include volatile anesthetics, nitrous oxide, and opioids.

Purpose:

  • To clarify the role of various pathophysiological mechanisms in PONV.
  • To identify patient-specific risk factors for PONV.
  • To establish a rational basis for risk-dependent antiemetic prophylaxis and treatment.

Summary:

  • Patient-specific risk factors like female gender, non-smoking status, and history of motion sickness or PONV enable objective risk assessment.
  • Prophylactic strategies should be risk-dependent: no intervention for low risk, single intervention for moderate risk, and combination therapy for high risk.

Related Experiment Videos

  • Total intravenous anesthesia (TIVA) with propofol offers some prophylaxis but is insufficient alone for high-risk patients; metoclopramide is ineffective for PONV.

    • Impact:

    • Risk stratification allows for personalized antiemetic approaches, optimizing prophylaxis and treatment efficacy.
    • Understanding risk factors can guide the selection of appropriate prophylactic and therapeutic antiemetic agents.
    • This approach aims to reduce the incidence and severity of PONV, improving patient outcomes.