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Updated: Aug 23, 2026

Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
In vitro coronary artery imaging with sixteen-slice helical computed tomography
F Knollmann1, C A Yankah, U Kaisers
1Department of Radiology and Anesthesiology, Charité, Campus Virchow-Klinikum, Berlin, Germany. Friedrich.Knollmann@charite.de
Purpose:
To determine the benefits of submillimeter coronary computed tomography (CT) angiography in vitro.
Material And Methods:
The coronary arteries of three domestic pigs were filled with contrast agent and depicted with clinically applicable CT angiography protocols with a slice thickness of 0.63 to 2.5 mm.
Results:
With 2.5 mm slices, only the third-degree coronary artery branches could be discerned. With 1.25 mm slices, some fourth-degree branches of the right coronary artery could be discerned upon maximum intensity projections. With 0.63mm slices, fourth-degree coronary artery branches could be discerned in all locations.
Conclusion:
The introduction of 16-row detector CT with submillimeter z-axis resolution translates into an order-of-magnitude benefit for the depiction of coronary artery branches.
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