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Updated: Aug 23, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Evolving immunotherapeutic strategies in bladder and renal cancer
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester General Hospital, Leicester, UK. TRLG1@le.ac.uk
Abstract:
For patients with urological cancers, immunotherapy is currently a treatment option for metastatic renal cell carcinoma, and those with "high risk" superficial bladder cancers. In this review, our current understanding of tumour immune escape is discussed. The principles and role of current immunotherapies for these tumours are described, and new areas of immunotherapeutic promise are highlighted.
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