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Squash smear findings of spherical amyloid in pituitary prolactinoma. A case report
Se Hoon Kim1, Sun Ho Kim, Seung-Koo Lee
1Department of Pathology, College of Medicine, Yonsei University, Seoul, South Korea.
Background:
Pituitary prolactinoma containing spherical amyloid is rare. Squash smear findings of spherical amyloid in pituitary prolactinoma are characteristic.
Case:
A 25-year-old woman presented with a pituitary tumor. The intraoperative squash smear showed abundant, homogeneous, eosinophilic material with multiple prominent striations. The scattered atypical cells in the periphery contained an irregular, bizarre nucleus; coarse chromatin; occasional prominent nucleoli; rare cytoplasm; and prolactin immunoreactivity.
Conclusion:
The characteristic squash smear findings should be helpful in the diagnosis of this rare tumor.
