Related Experiment Video
Updated: Aug 23, 2026

05:32
Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model
Published on: August 11, 2023
Modest follicle-stimulating hormone elevations in younger women: warn but don't disqualify
1Atlanta Center for Reproductive Medicine, Woodstock, Georgia 30189, USA. Jim.Toner@acrm.com
Fertility and Sterility
|June 15, 2004
Abstract:
Markers of quantitative defects in egg production (low ovarian reserve) have often been used to exclude patients from treatment, even when egg quality is apt to be satisfactory. Women younger than 38 years of age with modest FSH elevations (10-15 or even 20 IU/L) have acceptable pregnancy rates despite their limited production of eggs ("quality matters more than quantity") and so should be given the opportunity to try IVF.
Related Concept Videos
Oogenesis
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Folliculogenesis
Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
