Related Experiment Videos
Sperm tail agenesis in a case of consanguinity
Maurizio Latini1, Loredana Gandini, Andrea Lenzi
1Department of Medical Pysiopathology, University of Rome "La Sapienza.",Rome, Italy. maurizio.latini@uniroma1.it
Objective:
To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity.
Design:
Case report.
Setting:
University-based andrology clinic.
Patient(S):
A 27-year-old man undergoing infertility evaluation.
Intervention(S):
None.
Main Outcome Measure(S):
Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood.
Result(S):
One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy.
Conclusion(S):
A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.