Takayasu arteritis of subclavian artery in a Caucasian

Area of Science:

• Cardiology
• Rheumatology
• Immunology

Background:

• Takayasu arteritis is an inflammatory, obliterative disease of medium and large arteries, often affecting the aorta and its branches.
• It is classified as a giant cell arteritis and can present with systemic symptoms mimicking other conditions.
• While historically associated with specific demographics, it is now recognized globally.

Observation:

• A Caucasian woman presented with nonspecific symptoms including fatigue and upper back pain.
• Physical examination revealed an absent left radial pulse and a significant blood pressure differential.
• Radiological imaging confirmed left subclavian artery stenosis.

Findings:

• The patient's presentation and imaging findings were consistent with Takayasu arteritis.
• This case underscores that Takayasu arteritis affects diverse populations, not limited by ethnicity or origin.
• Early diagnosis relies on clinical suspicion, physical findings, and advanced imaging.

Implications:

• Prompt diagnosis and management are crucial to prevent severe vascular complications.
• This case contributes to the understanding of Takayasu arteritis presentation in non-traditional demographics.
• Further research into the autoimmune etiology may reveal novel therapeutic targets.