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Transcriptional control of synaptic differentiation by retrograde signals

Anna Kalinovsky1, Peter Scheiffele

  • 1Columbia University, Department of Physiology and Cellular Biophysics, 630 West 168(th) Street, P&S 11-511, New York, New York 10032, USA.

Current Opinion in Neurobiology
|June 15, 2004
PubMed

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Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
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