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Development of an analytical method for 3-monochloropropane-1,2-diol in soy sauce using 4-heptanone as derivatizing
Fabian M Dayrit1, Milady R Niñonuevo
1Department of Chemistry, Ateneo de Manila University, Loyola Heights, Quezon City, 1108 Philippines. fdayrit@ateneo.edu
Abstract:
3-Monochloro-1,2-propane diol is a suspected carcinogen found in hydrolysed vegetable protein products such as soy sauce. A method is described for the analysis of 3-monochloro-1,2-propane diol in soy sauce by gas chromatography-mass spectrometry at a concentration range of 1-5000 ng g-1 using 4-heptanone as the derivatizing ketone and 3-monochloro-1,2-propane diol-d5 as the internal standard. The limit of detection for the method in the soy sauce matrix was 0.48 ng g-1 and the limit of quantification was 1.2 ng g-1.
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