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Optimizing medication adherence in older persons with hypertension.

William J Elliott1

  • 1The Department of Preventive Medicine, RUSH Medical College of RUSH University at RUSH University Medical Center, Chicago, IL 60612, USA. welliott@rush.edu

International Urology and Nephrology
|June 17, 2004
PubMed
Summary

Many patients stop taking blood pressure medication within a year. Simple, well-tolerated, once-daily regimens and patient education are key to improving medication adherence for better hypertension control.

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Area of Science:

  • Cardiology
  • Pharmacology
  • Public Health

Background:

  • Suboptimal hypertension control affects large populations, with approximately 50% of patients discontinuing antihypertensive drugs within one year.
  • Older patients with multiple comorbidities, including chronic kidney disease, face a higher risk of medication non-adherence, with pill burden being a stronger predictor than age.

Purpose of the Study:

  • To explore factors influencing medication adherence in hypertension management.
  • To identify effective strategies for improving patient adherence to antihypertensive therapies.

Main Methods:

  • Review of clinical practice observations and interventional trials regarding medication adherence.
  • Assessment of simple patient-reported adherence questions and the impact of regimen characteristics.

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Main Results:

  • Clinical trials often do not reflect real-world medication adherence challenges.
  • Short, simple, well-tolerated, and inexpensive medication regimens are more likely to be taken as prescribed.
  • Patient and family education, simplified regimens, and prompts linked to daily activities enhance adherence.

Conclusions:

  • Improving medication adherence is crucial for effective hypertension management and cost-effectiveness of treatments.
  • A multifaceted approach involving patient education, regimen simplification, and family involvement is necessary to improve adherence.
  • No single intervention guarantees adherence, but combined strategies offer significant benefits.