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Papillary microcarcinoma of the thyroid gland: analysis of prognostic factors including histological subtype
Laura Falvo1, Claudia D'Ercole, Salvatore Sorrenti
1Division of General Surgery, Department of Surgical Sciences, "La Sapienza" University of Rome, Rome, Italy. laurafalvo@mclink.it
Objective:
To evaluate the prognosis of papillary microcarcinoma (PMC) of the thyroid.
Design:
Prospective study.
Setting:
Teaching hospital, Italy.
Subjects:
89 patients treated for papillary micro carcinoma of thyroid and followed up for at least 6 years (range 6-12).
Intervention:
Total thyroidectomy and, for lymph node metastases, laterocervical lymphadenectomy.
Main Outcome Measures:
Sex distribution, mode of onset of disease, diameter of tumour, histological type, histological stage, presence of lymph node metastases at the time of operation and type of operation.
Results:
When the disease presented with laterocervical lymph nodes it was histologically more aggressive and included follicular (n = 3) and sclerosing (n = 4) types.
Conclusion:
Papillary microcarcinoma has an excellent prognosis if managed initially by total thyroidectomy.
