[Polyneuritis cranialis HHV-6 infection associated]
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Updated: Aug 23, 2026

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
Published on: April 2, 2012
Diego Brustia1, Alessia Uglietti, Pietro Luigi Garavelli
1SCDO Malattie Infettive, Azienda Sanitaria Ospedaliera Maggiore della Carità, Novara.
Abstract:
Human herpesvirus 6 (HHV-6) has been shown to be a common cause of acute febrile disease in young children, including exanthema subitum. HHV-6 has also been associated with a number of neurologic disorders including encephalitis and the virus has been postulated to play a role in acquired immunodeficiency syndrome, multiple sclerosis and chronic fatigue syndrome. The disorder of multiple cranial nerve palsies without spinal cord involvement is referred to as polyneuritis cranialis and is rare. The Authors describe a case of polyneuritis cranialis in a 52-year old woman treated with ganciclovir and only complete eradication of the virus.
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