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Updated: Aug 23, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Chronic cor pulmonale: a rare complication of undiagnosed pacemaker lead endocarditis
Abstract:
Pacemaker lead infection is a rare life-threatening complication of permanent transvenous pacing. We describe the case of a young man who suffered recurrent undiagnosed septic pulmonary embolisms from pacemaker lead vegetations inducing chronic cor pulmonale with major pulmonary arterial hypertension. The potential complications of transvenous pacing and the systematic use of transesophageal echocardiography are emphasized.
Insights
Pacemaker lead infections, though rare, can cause serious lung and heart problems. Early diagnosis using transesophageal echocardiography is crucial for managing these life-threatening complications.
Area of Science:
- Cardiology
- Infectious Diseases
- Pulmonology
Background:
- Permanent transvenous pacing is a common medical procedure.
- Pacemaker lead infection is a rare but severe complication.
- Septic pulmonary embolisms can arise from infected pacemaker leads.
Observation:
- A young man presented with recurrent, undiagnosed septic pulmonary embolisms.
- These embolisms originated from pacemaker lead vegetations.
- The patient developed chronic cor pulmonale and pulmonary arterial hypertension.
Findings:
- Pacemaker lead vegetations were identified as the source of septic emboli.
- The patient's condition led to significant pulmonary hypertension and heart strain.
- Undiagnosed infections can have devastating consequences.
Implications:
- Highlights the critical need for vigilance regarding pacemaker lead infections.
- Emphasizes the importance of transesophageal echocardiography in diagnosing lead-related complications.
- Underscores the potential for severe cardiopulmonary sequelae from undetected pacemaker infections.
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