Damage limitation in burn surgery
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Updated: Aug 23, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
Tim La H Brown1, Michael J Muller
1South Auckland Burns Service, Middlemore Hospital, P.O. Box 93311, Otahuhu, Auckland, New Zealand. timbrown@middleore.co.nz
Abstract:
Burn injury differs from other types of trauma in the apparent lack of urgency for treatment. We argue that in order to limit physiological damage and the development of multi-organ failure, management of the burn wound must be immediate and aggressive. Supportive fluid treatment should be judicious in order to prevent excessive oedema causing wound extension. Some potential strategies utilising oral fluid resuscitation are discussed, and potential pharmacological interventions. When associated with other trauma, major burn injury has a detrimental effect on morbidity and mortality, and surgical management of both aspects of a patient's injuries are altered.
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