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Published on: June 29, 2022
Recurrent atrial ectopic tachycardia following chemotherapy with ifosfamide
Lars Müller1, Christof M Kramm, Wolfgang Lawrenz
1Department of Pediatric Hematology, Oncology and Immunology, University Medical Center, Heinrich-Heine-University, Düsseldorf, Germany.
Abstract:
In most pediatric tumors, particularly sarcomas, cyclophosphamide or ifosfamide represent essential first-line chemotherapeutic agents. Whereas cyclophosphamide is known to be associated with a well-defined cardiomyopathy, only a few cardiac complications following ifosfamide chemotherapy have been observed to date. Here we report a patient treated for Ewing sarcoma with multiple pulmonary and osseous metastases who repeatedly developed a supraventricular tachyarrhythmia following administration of ifosfamide as part of a polychemotherapy regimen.
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