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Anthony Dipple Carcinogenesis Award. p53 from pathway to therapy
1Department of Surgery and Molecular Oncology, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK. d.p.lane@dundee.ac.uk
Carcinogenesis
|June 19, 2004
Abstract:
In the 25 years since its first description the p53 protein has been shown to play a key role in both tumour suppression and aging. New discoveries about the function and control of p53 continue to emerge every month and attempts to exploit the system to develop better therapeutics and diagnostics are beginning to be successful in the clinic.