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Updated: Aug 23, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
Published on: January 7, 2018
[Disorder of carbohydrate metabolism]
Takehiro Nakamura1, Hiroshi Sakaue, Masato Kasuga
1Division of Diabetes, Digestive and Kidney Diseases, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine.
Abstract:
The worldwide epidemic of type 2 diabetes and impaired glucose tolerance is a crucial health problem. Since disorder of carbohydrate metabolism causes arteriosclerosis in combination with other metabolic abnormalities such as hypertension, hyperlipidemia and obesity, it has now been recognized as one manifestation of the metabolic syndrome, a condition characterized by insulin resistance. In this article, we summarize the current our knowledge on how disorder of carbohydrate metabolism influences insulin resistance and arteriosclerosis in part of metabolic syndrome.
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