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The use of testosterone after menopause
1Department of Obstetrics and Gynaecology, Monash University, Clayton, Australia.
The Journal of the British Menopause Society
|June 23, 2004
Summary
Testosterone therapy can enhance sexual satisfaction and mood in surgically menopausal women. However, long-term safety and effects of testosterone-only therapy in postmenopausal women require further investigation.
Area of Science:
- Endocrinology
- Women's Health
- Menopause Management
Background:
- Substantial evidence supports testosterone therapy's benefits for sexual satisfaction and mood in surgically menopausal women on estrogen.
- Limited data exist for naturally menopausal and premenopausal women.
Purpose of the Study:
- To review the evidence for testosterone therapy in postmenopausal women.
- To highlight the need for long-term safety data and understanding of testosterone-only therapy.
Main Methods:
- Review of randomized controlled trials and existing literature on testosterone therapy in menopausal women.
Main Results:
- Testosterone therapy improves sexual satisfaction and mood in surgically menopausal women receiving concurrent estrogen.
- Long-term safety data for combined estrogen-testosterone therapy are lacking.
- Effects of testosterone-only therapy in postmenopausal women remain unknown.
Conclusions:
- Testosterone holds potential for improving quality of life in selected postmenopausal women.
- Inappropriate or excessive testosterone use risks masculinization and other adverse effects.
- Careful biochemical and clinical monitoring, with long-term follow-up, is essential for all women receiving testosterone therapy.