Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

SARS exposure and emergency department workers.

Wei-Tien Chang1, Chuan-Liang Kao, Ming-Ya Chung

  • 1Department of Laboratory Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan. hsporen@ha.mc.ntu.edu

Emerging Infectious Diseases
|June 23, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The emergence and successful elimination of SARS-CoV-2 dominant strains with increasing epidemic potential in Taiwan's 2021 outbreak.

Heliyon·2023
Same author

Reply to: Real-time audiovisual feedback during CPR: A clarification, meta-analysis update, and caution for interpretation.

Resuscitation·2020
Same author

Effects of real-time feedback on cardiopulmonary resuscitation quality on outcomes in adult patients with cardiac arrest: A systematic review and meta-analysis.

Resuscitation·2020
Same author

Inter- and intra-host sequence diversity reveal the emergence of viral variants during an overwintering epidemic caused by dengue virus serotype 2 in southern Taiwan.

PLoS neglected tropical diseases·2018
Same author

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

Human molecular genetics·2016
Same author

Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.

Nature communications·2016

Severe acute respiratory syndrome (SARS) infected 4.7% of exposed emergency department workers. Most infected workers developed pneumonia or mild symptoms, indicating occupational risk for healthcare professionals.

Area of Science:

  • Infectious Diseases
  • Occupational Health
  • Virology

Background:

  • Severe Acute Respiratory Syndrome (SARS) poses a significant occupational risk to healthcare workers.
  • Understanding transmission dynamics and infection rates in emergency departments is crucial for public health.
  • Previous outbreaks highlight the vulnerability of frontline medical staff.

Purpose of the Study:

  • To determine the infection rate of SARS among emergency department (ED) workers following exposure.
  • To characterize the clinical presentation and serological response in infected ED personnel.
  • To assess the occupational risk associated with SARS exposure in an acute care setting.

Main Methods:

  • Prospective cohort study of 193 emergency department workers with documented SARS exposure.

Related Experiment Videos

  • Clinical assessment including symptom evaluation and diagnosis of pneumonia.
  • Serological testing for severe acute respiratory syndrome-specific immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies.

    • Main Results:

    • A total of 9 out of 193 (4.7%) exposed ED workers were infected with SARS.
    • Six infected workers developed pneumonia, confirmed by serological assays showing anti-SARS IgM and IgG.
    • The remaining three infected workers were IgM-positive with lower IgG titers; two experienced mild illness, and one was asymptomatic.

    Conclusions:

    • Emergency department workers face a notable risk of SARS infection following occupational exposure.
    • Clinical manifestations of SARS infection in healthcare workers can range from asymptomatic to severe pneumonia.
    • Robust infection control measures are essential to protect healthcare professionals during outbreaks.