Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Elements and Compounds01:27

Elements and Compounds

105.3K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
105.3K
Molecular Shape and Polarity03:37

Molecular Shape and Polarity

76.0K
Dipole Moment of a Molecule
76.0K
Periodic Classification of the Elements04:00

Periodic Classification of the Elements

59.6K
The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
59.6K
Conjugated Proteins02:50

Conjugated Proteins

29.0K
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
29.0K
Genomics02:02

Genomics

40.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.9K
Classification of Elements and Compounds02:54

Classification of Elements and Compounds

73.6K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units.
Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
73.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The cholesterol-dependent cytolysin promotes <i>Streptococcus</i> systemic spread and induces arachidonic acid accumulation-mediated lethality in a murine intraperitoneal infection model.

Infection and immunity·2026
Same author

IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice.

Nature microbiology·2026
Same author

Remodeling of tRNA modification in Trypanosoma cruzi life forms.

PLoS pathogens·2026
Same author

Early-life Wnt4 expressing colon stromal cells orchestrate lifelong mucosal homeostasis via BMP-driven iNKT cell imprinting.

Nature communications·2026
Same author

A pro-carcinogenic bacterial toxin binds claudin-4 to cleave E-cadherin.

Nature·2026
Same author

IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Feb 12, 2026

High-Resolution Comparison of Bacterial Conjugation Frequencies
05:18

High-Resolution Comparison of Bacterial Conjugation Frequencies

Published on: January 10, 2019

11.5K

Shaping bacterial genomes with integrative and conjugative elements.

Vincent Burrus1, Matthew K Waldor

  • 1Department of Molecular Biology and Microbiology, Tufts University School of Medicine, and Howard Hughes Medical Institute, 136 Harrison Avenue, Boston, MA 02111, USA. vincent.burrus@tufts.edu

Research in Microbiology
|June 23, 2004
PubMed
Summary
This summary is machine-generated.

Integrative and conjugative elements (ICEs) are mobile genetic elements that facilitate gene transfer in prokaryotes. These elements drive bacterial adaptation and evolution by spreading diverse functions, including antibiotic resistance and virulence genes.

More Related Videos

Creation of a Dense Transposon Insertion Library Using Bacterial Conjugation in Enterobacterial Strains Such As Escherichia Coli or Shigella flexneri
11:36

Creation of a Dense Transposon Insertion Library Using Bacterial Conjugation in Enterobacterial Strains Such As Escherichia Coli or Shigella flexneri

Published on: September 23, 2017

16.7K
Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach
11:12

Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach

Published on: September 11, 2017

8.0K

Related Experiment Videos

Last Updated: Feb 12, 2026

High-Resolution Comparison of Bacterial Conjugation Frequencies
05:18

High-Resolution Comparison of Bacterial Conjugation Frequencies

Published on: January 10, 2019

11.5K
Creation of a Dense Transposon Insertion Library Using Bacterial Conjugation in Enterobacterial Strains Such As Escherichia Coli or Shigella flexneri
11:36

Creation of a Dense Transposon Insertion Library Using Bacterial Conjugation in Enterobacterial Strains Such As Escherichia Coli or Shigella flexneri

Published on: September 23, 2017

16.7K
Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach
11:12

Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach

Published on: September 11, 2017

8.0K

Area of Science:

  • Microbiology
  • Genetics
  • Molecular Biology

Background:

  • Integrative and conjugative elements (ICEs) are self-transmissible mobile genetic elements crucial for lateral gene flow in prokaryotes.
  • ICEs share characteristics with temperate bacteriophages and conjugative plasmids, integrating into the genome and transferring to new hosts.

Purpose of the Study:

  • To elucidate the multifaceted roles of ICEs in bacterial adaptation and genome evolution.
  • To highlight the diverse functions mediated by ICEs beyond antibiotic resistance gene transfer.

Main Methods:

  • Comparative genomics analysis of mobile genetic elements.
  • Bioinformatic identification and characterization of ICE backbone modules and accessory genes.
  • Review of existing literature on ICE function and impact.

Main Results:

  • ICEs possess a conserved backbone for maintenance, dissemination, and regulation, capable of acquiring additional genes via mobile genetic modules.
  • ICEs mediate the transfer of a wide array of functions, significantly contributing to bacterial adaptation to new environments and niches.
  • ICEs play a substantial role in shaping bacterial genomes, promoting strain variability, and facilitating inter-generic gene distribution.

Conclusions:

  • ICEs are key drivers of bacterial evolution, adaptation, and niche colonization through horizontal gene transfer.
  • ICEs contribute to the spread of important traits, including antibiotic resistance and virulence factors.
  • ICEs may also promote the mobilization of genomic islands by utilizing conserved integration sites.