Differential cerebral and neuropsychological consequences in dizygotic twins with prenatal alcohol exposure
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Published on: July 13, 2014
A Narberhaus1, D Segarra, M Giménez
1Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Passeig de la Vall d'Hebron 171, E-08035, Spain.
Aim:
To relate structural and functional findings in one adolescent dizygotic twin pair with prenatal alcohol exposure.
Method:
Neuropsychological and volumetric magnetic resonance studies were carried out on a 13-year-old preterm dizygotic twin pair with prenatal alcohol exposure.
Results:
Neuropsychological and brain structural findings differed between the twins. The child with the more affected phenotype had large-scale cognitive deficits and presented significant atrophy in several brain structures. Both subjects had white matter volume reductions relative to the whole cerebral volume.
Conclusion:
The neuropsychological and neuroimaging data reflect long-term consequences of prenatal alcohol exposure.
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