Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postsynaptic potentials in cat visual cortex: dependence on polarization.

M Volgushev1, X Pei, T R Vidyasagar

  • 1Department of Neurobiology, Max-Planck-Institute for Biophysical Chemistry, Göttingen-Nikolausberg, Germany.

Neuroreport
|August 1, 1992
PubMed
Summary

Investigating visual cortical neurons revealed that postsynaptic potentials (PSPs) deviate from standard models. Voltage-dependent ion channels likely influence these excitatory and inhibitory responses to visual stimuli.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nano-Driven Dual Ferroptosis Inhibition for Diabetic Periodontitis Therapy.

Journal of dental research·2026
Same author

Probiotic enhanced immunity and mental wellbeing of generally healthy women: a randomised, placebo-controlled and double-blind study.

Beneficial microbes·2025
Same author

Role of Cisplatin in Inducing Acute Kidney Injury and Pyroptosis in Mice via the Exosome miR-122/ELAVL1 Regulatory Axis.

Physiological research·2024
Same author

Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring.

Human & experimental toxicology·2022
Same author

APOBEC mutagenesis, kataegis, chromothripsis in EGFR-mutant osimertinib-resistant lung adenocarcinomas.

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same author

Dynamics of coherent activity between cortical areas defines a two-stage process of top-down attention.

Experimental brain research·2021

Area of Science:

  • Neuroscience
  • Electrophysiology

Background:

  • Investigating visually evoked postsynaptic potentials (PSPs) in visual cortical neurons.
  • Observed inconsistencies with the conventional understanding of PSPs based on membrane potential levels.

Purpose of the Study:

  • To analyze the unconventional dependence of PSPs on membrane polarization.
  • To explore the role of voltage-dependent ion channels in visual cortical neuron responses.

Main Methods:

  • Recording cell activity of visual cortical neurons.
  • Manipulating membrane potential to observe PSP changes.

Main Results:

  • Excitatory potentials decreased during hyperpolarization, contrary to expectations.
  • Depolarization increased the amplitude of both excitatory and inhibitory PSPs.

Related Experiment Videos

  • These findings suggest the involvement of voltage-dependent ion channels.

    • Conclusions:

    • The conventional scheme for PSPs is insufficient for visual cortical neurons.
    • Voltage-dependent ion channels play a significant role in visual processing.
    • Methods for separating excitatory and inhibitory components despite these channels are discussed.