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Related Experiment Videos

Using genomic databases for sequence-based biological discovery.

Andreas D Baxevanis1

  • 1Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20852, USA. andy@nhgri.nih.gov

Molecular Medicine (Cambridge, Mass.)
|June 23, 2004
PubMed
Summary
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Biologists need tools to navigate vast genomic data. This review covers key resources like LocusLink and major genome browsers for efficient sequence information discovery.

Area of Science:

  • Genomics
  • Bioinformatics

Background:

  • The International Human Genome Sequencing Consortium and other projects have generated immense sequence data.
  • The rapid increase in sequence information necessitates effective data navigation skills for biologists.

Purpose of the Study:

  • To review commonly used tools for sequence discovery and information mining.
  • To guide biologists in navigating the expanding 'sequence information space'.

Main Methods:

  • Discussion of LocusLink for gene-centric sequence information.
  • Overview of major genome browsers: NCBI Map Viewer, UCSC Genome Browser, and Ensembl.
  • Information on available data types and user documentation for these tools.

Main Results:

Related Experiment Videos

  • Identified LocusLink as a valuable gene-centric resource.
  • Highlighted the utility of NCBI Map Viewer, UCSC Genome Browser, and Ensembl for genome-wide exploration.
  • Provided insights into accessing tutorials and documentation for enhanced user familiarity.

    • Conclusions:

    • Effective use of bioinformatics tools is crucial for modern biological research.
    • Resources like LocusLink and genome browsers empower biologists to extract meaningful insights from large-scale sequence data.