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Updated: Aug 23, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
[Cardiogenic shock in acute coronary syndrome--therapeutic approach]
Vjeran Nikolić Heitzler1, Zdravko Babić, Sime Manola
1Koronarna jedinica, Zavod za kardiovaskularne bolesti Interne klinike, Klinicka bolnica Sestre milosrdnice, Vinogradska 29 10000 Zagreb, Hrvatska.
Insights
Primary percutaneous coronary intervention (PCI) significantly reduces mortality in acute ST-elevation myocardial infarction (STEMI) patients experiencing cardiogenic shock. This vital treatment lowers the death rate from 80% to 35% in STEMI cases.
Area of Science:
- Cardiology
- Interventional Cardiology
Context:
- Cardiogenic shock is a severe complication of acute coronary syndromes.
- Mortality rates for cardiogenic shock have historically been high, especially with conservative treatment.
Purpose:
- To assess the incidence and mortality rates of cardiogenic shock in patients with ST-elevation myocardial infarction (STEMI).
- To evaluate the effectiveness of primary percutaneous coronary intervention (PCI) in treating STEMI-induced cardiogenic shock.
Summary:
- The study included 701 STEMI patients, with 312 treated with primary PCI.
- The incidence of cardiogenic shock among STEMI patients was found to be 8.3%.
- Primary PCI reduced the mortality rate for cardiogenic shock in STEMI patients from 80% to 35%.
Impact:
- Primary PCI has emerged as the definitive therapy for cardiogenic shock complicating STEMI.
- This intervention significantly improves survival rates for a critical patient group.
- The findings support the widespread adoption of primary PCI in managing STEMI with cardiogenic shock.
Aim:
Cardiogenic shock is the most serious complication of acute coronary syndromes and cause of death in 4.2-7.2% of patients with acute ST-elevation myocardial infarction (STEMI), in 2.1% of patients with acute non-ST-elevation myocardial infarction and in 2.9% of patients with unstable angina pectoris. The cardiogenic shock mortality rate of 80% in patients treated conservatively has been decreased with the introduction of primary percutaneous coronary intervention (PCI) in the treatment of STEMI. The incidence and mortality rate were assessed in patients with cardiogenic shock treated with primary PCI at Department of Cardiovascular Diseases, Sestre Milosrdnice University Hospital.
Patients And Methods:
Since 2000, the emergency interventional cardiologic service has been available for 24 h at the Department. During this period, 701 patients were hospitalized with the diagnosis of STEMI, 312 of them meeting the recommended criteria, were treated with primary PCI.
Results:
According to study results, the incidence of cardiogenic shock in STEMI patients was 8.3%. Treatment with primary PCI decreased cardiogenic shock mortality rate to 35%.
Conclusion:
Primary PCI is definitely therapy of choice in the treatment of this serious complication of acute STEMI.
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