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[Inflammation markers in acute coronary syndrome]
Jure Mirat1, Miroslav Raguz, Zeljko Romić
1Zavod za bolesti srca i krvnih zila, Opća bolnica Sveti Duh, 10000 Zagreb, Hrvatska.
Abstract:
Inflammation is a component of atherosclerotic plaque, but it is also a possible pathogenetic factor of acute coronary event responsible for coronary instability. Inflammatory markers are considered as new risk factors for atherosclerosis. Among others (C-reactive protein (CRP) is the best known marker of inflammatory response which is most frequently found in patients with acute myocardial infarction preceded by a period of instability. High values of inflammatory markers indicate poor prognosis after acute myocardial infarction. Therapy may lower the inflammatory component and the risk of coronary disease. Specific response of inflammatory marker during diagnostic and percutaneous coronary interventions indicates more severe coronary disease.